- 5% of the US population is affected
by autoimmune diseases including:
- Multiple sclerosis
- Rheumatoid arthritis
- Type 1 diabetes
- Crohn’s Disease
- Hashimoto’s thyroiditis
- Lupus
- 9 out of 18 human clusters of autoimmune
susceptible genes share highly-conserved genetic regions
with animal models
- The major histocompatibility locus
(MHC) is one of the major susceptibility loci
- Environmental factors also contribute
to the onset of autoimmunity
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BRM, Inc., breeds
and performs research with several animal models of spontaneous
and environmentally-triggered autoimmune disorders including:
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