Metabolic Disease Phenotyping

Diabetes

• Steady-state Glucose
• Insulin ELISA
• Fasted Glucose/Insulin Tolerance Testing
• HbA1c Analysis*
• In-vivo acute (glucose/arginine) insulin secretion studies
• Ex-vivo glucose oxidation, lipolysis, and gluconeogenesis

*Dyslipidemia

• Lipid Profile - Cholesterol, triglycerides, HDL, LDL, VLDL

Obesity

• Food intake comparison
• Body mass composition analysis by necropsy
• Leptin/Ghrelin analysis
• Core body temperature

Metabolic Feeding Studies

• Pair-feeding studies
• Food consumption
• Liquid consumption
  * via subcontract agreement with a commercial anayltical laboratory