Biomedical Research Models, Inc. has unique expertise in
the development, production, and distribution of Proprietary
Animal Models of Human Disease.
 BRM’s
animal models facilitate the study of the pathogenesis
and
complications of
diseases, because they
permit the evaluation of treatment protocols
that are not immediately feasible or ethical in human
patients.
They
provide populations of genetically uniform subjects
that can be maintained under environmentally controlled
conditions.
Hence,
new pharmaceutical agents, dietary regimens etc. can
first be tested in animals, to evaluate potential toxicity
and therapeutic benefit prior to human application.
If one assumes that all animal models
have inherent limitations, then the use of multiple
experimental models
represents a useful strategy for evaluating new therapeutic
modalities for the study of disease and it's complications.
Our animal models are easily adapted for the testing
of compounds for a multitude of applications.
|
 BBDP/Wor
rat (Type I Diabetic: Spontaneous)
These animal models are usually
used for the studies of Spontaneous Type I (diabetes
mellitus and Hashimoto's thyroiditis) and diabetic complications.
BBDR/Wor rat
(Type I Diabetic: Induced) Diabetic Resistant (DR) controls
for DP rats.
This animal is also a model
of viral induced diabetes (Science 254:1010) and collagen
induced arthritis (J. Exp.Med. 172:1331)
BBZDR/Wor rat (Type II Diabetic)
The
BBZDR/Wor rats are animal models of Non-Insulin Dependent
Diabetes Mellitus (NIDDM), insulin resistance, obesity,
hypertension, dyslipidemia, and diabetic vascular complications.
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