 For your virology needs, BRM
can offer:
 Expertise in herpesviruses, parvoviruses,
hepatitis viruses, vaccinia virus, measles virus
and rotaviruses
- BSL 2 facility for housing and manipulation
of animals, including surgical procedures.
- Individual
isolators dedicated to each experiment
- Serological
testing of animals
- Multiple rat models of virus-induced
diabetes which can be provided at any stage of
disease development
- KRV-induced diabetes in BBDR/Wor
- KRV-induced diabetes in LEW.1WR1
- RCMV-induced diabetes in LEW.1WR1
- Design and perform
experiments to test efficacy of client’s
compounds in ameliorating the symptoms of diabetes
induced by
viruses
- Full necropsy
including blood chemistry profiles, sectioning
and H&E staining of chosen organs.
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BRM
employs fully trained virologists to design and implement
a variety of experiments for
your in vivo animal studies.
Research Director, Dr.
Rebecca Tirabassi, can work with you to design
experiments tailored to your needs.
All
experiments are performed with biosafety level 2 (BSL
2) practices and animals are housed in individual isolators
to prevent cross contamination of pathogens.
We are experts on
virus-induced models of diabetes.
Dennis
Guberski, the president and cofounder of the company,
was one of the first investigators to describe and
characterize the induction of diabetes by the rat parvovirus,
Kilham’s Rat Virus (KRV).
In addition, BRM has
developed an exciting new
model of diabetes induction after infection with
rat cytomegalovirus (RCMV).
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